"The first truth, brothers, is the fact of suffering. All desire happiness, sukha: what is good, pleasant, right, permanent, joyful, harmonious, satisfying, at ease. Yet all find that life brings duhkha, just the opposite: frustration, dissatisfaction, incompleteness, suffering, sorrow. Life is change, and change can never satisfy desire. Therefore everything that changes brings suffering." -- Siddhartha Gautama