Just for you console-rs: BIO is the combo lock on the second floor. RES is the combo lock on the third floor.
I couldn't find anything to remove the jack for the infamous library, and keeping the boards doesn't do anything. I haven't tried going back the long way to Marvin to see if they do anything in the demo beyond boarding up certain windows (like the shutters in the original).
I'm pretty impressed with what the team has done. On one hand, it triggers my purist/old-school fanboy anger, but on the other (with an open-mind) the 7 engine is delivering a near-faithful experience (in terms of limited item storage, zombies being a "threat" but also being dumb enough to where you can stand still for a minute to get the critical shot bonus like the tank-ready-shoot system) to where I'm pretty happy with what we've got, but I really REALLY wish Capcom would give a fixed-angle mode to me.