Holy shit. That good?
KB or did you bother remapping controls to a gampad, Joe?
Keyboard only.
spoiler (click to show/hide)
No items. Final Destination.
Did another playthrough and took some screenshots (spoilers if you want to discover all the crazy new stuff for yourself)
spoiler (click to show/hide)
(http://i.imgur.com/Li5fV.jpg)
Nice to see the good ol' zero health devil room glitch is still around.
(http://i.imgur.com/mzwRi.jpg)
Sometimes instead of a devil room, you get an angel room.
(http://i.imgur.com/zyMVX.jpg)
New final area is the Cathedral, at the end of the Womb you get a choice of whether to ascend into heaven or descend into Sheol. I made it to the final final boss (and died) and no, it's not who you think and that's all I'm gonna say. :p