Did an HD version of Primer come out or something? What's ignited your interest in it?
Primer deals with the intricacies of time travel in such a minute, detailed way that it's easy to miss what's going on (particularly if intoxicated). I've watched it sober and drunk any number of times, and I still doubt I could really explain the whole thing. So maybe it really doesn't much matter what state you watch it in....you'll probably need to consult an FAQ either way. But then again you watch plot details better than I do, so perhaps you will fare better. At the moment, I'd say it's somewhat like Donnie Darko, only in that important aspects of the plot are simply not communicated to the viewer, no matter how astute that viewer might be.