Oh man, it could be a direct sequel. Have them move to England instead, to Dustin Hoffman's old house. The English people resent Rambo because they remember what happened the last time an American lived in that house. Eventually Rambo meets Hoffman's wife from the first movie and she tells him what happened and then tries to kill him. His 'Nam self-defense skills kick in and he accidentally kills her, which makes the townspeople go nuts and all of them lay a siege on the house. Now Rambo must defend himself, his new wife, and their newborn baby.