If you ever want to feel really fucked up, like, deliberately throw yourself into a spiritual disease sort of fucked up, then eat a handful of shrooms, a couple of pills, drink a strong tonic and then finish it off with three lines of Ketamine. Try and space it out over an hour or so. Your back yard will have never appeared more alien and hostile.
Now, LSD to me is almost as bad. I'm almost scared of it.