I wrote this before until I realized you weren't asking for recommendations in general and then removed it. But since the thread has turned into that anyway, might as well repost it.
Coming from someone else who generally hates anime and japafags...
Cromartie High School if you like Adult Swim type humor ala Sealab, Aqua Teen HF. Truly inspired.
The Ping Pong Club for South Park type humor (before South Park was topical)
Serial Experiments Lain for mystical shit
Most of the rest I've seen is poop. Actually, an episode I've seen of Gantz looked intriguing, but I never bothered buying it. Maybe some day. All the usual "anime recommendations for people who don't like anime" you'd see on GAF and similar places are 95% of the time things only a full blown anime dork and/or 18-year old would enjoy, like Berserk and Samurai Champloo and Rurouni Kenshin that kind of juvenile angsty sword garbage. They're just trying to ensnare you into their hive. Don't fall into their trap, man. Stay strong.
