FFXIII, Gears 2, Infamous, Little Big Planet, RE5, Fat Princess, and Mirror's Edge. There's a bunch of things a tier below that-- like Banjo, Fable, Resistance, and Fallout. IU and SO4 are also cool looking, but IU's gameplay impressions have me a little uncertain at this point.
Fallout...I'm just not sold on. In fact, I was kind of more sold on it before E3.
Oh man, there really is too much to list...
Dead Space
Persona 4
Prince of Persia
NOT STREET FIGHTER 4 UNDER ANY CIRCUMSTANCES