Here's some quick notes from the Rage demonstration:
-Graphics are WOW. Maybe even Crysis good
-Worlds looks and feels a lot like Fallout, but maybe with a bit more life to it
-Fallout 3 was about 75% RPG and 25% FPS, Rage looks to be about 75% FPS and 25% RPG
-Nothing shown about characters stats/levelling
-You start out with a four-wheeler, and move your way up to dune buggies and cars. According to the developer, it's a challenge to get new and better vehicles.
-Lots of vehicle customization: different types of vehicles and weapons
-NPC voice acting and animation completely blow Fallout 3 out of the water
-Lots of vehicular combat
-You can use parts collected in the world to make bomb-carrying RC cars, turrets, and spider sentries and other things
-MUTANT BASH TV
-BOOMERANGS and THROWING KNIVES
-World looks to be built around moving from place to place using your vehicle
-When you travel, bandit gangs will attack you in there vehicles
-Self-shadowing is really good looking
It looked really, really good.