I took a class on Office 2007 back in April. Thought it was pretty easy to use, with the exception of doing more complex stuff like embedding a Youtube video in Powerpoint. Sadly most of the class failed (having to make a five-minute Powerpoint presentation was just too much, I guess, because over half the class didn't show up from that point on). I could have taken a test to exempt it, but I didn't know jack and squat about Excel. Plus it provided many comical moments of ghetto-foolishness.
I'm also taking a course on databases that uses Access 2007 right now, which is so BORING. I don't think databases are for me. Also while CISCO peeps seem to make more cash, I think I'd rather stay on the MS route.