My [female] Shepard marries Liara and they live happily ever after with a litter of squid-babies. Deal with it, Bioware.
It just seems really weird that in the midst of a SPRAWLING SPACE OPERA with a battle to save the universe from destruction by a race of sentient machines from beyond all time and space that they're going to cram in a story about tolerance of sexual preferences. An odd medium for it, is how it comes across. But, again, I've got my path mapped out already.