Physx is totally useless in the pc version considering it's not even noticeable unless you stop, pick up a weapon, point it, and shoot to see some funky cloth tears. It's not fucking revolutionary.
On the actual gameplay front, it must absolutely be played with a goddamn gam-pad (my preference was for the 360 one). In that sense at least, the two versions are equal but those screens do look sharp. Resolution and AA never seemed to be a problem on the consoles with this game's graphical style but I'm sure all versions were 60 fps.