Even on Casual difficulty, there are Activities which are just infeasible. The Repo Man/Tow Truck one, in particular, is just about impossible unless you play it in Co-op, and have your partner drive the car while you drive the tow truck separately.
At least, even with my highly tuned driving-and-shooting OWG spider-sense and mega-powers, it was the only way Scenester and I were able to complete it.