I haven't played it yet, but from impressions it seems like it suffers from the open world itis that has been spreading in Ubisoft and other games of late. Big world full of meaningless stuff and quests. Bit like an offline MMO.
Edit: Don't want to shit up your ME thread sorry.
On topic, I hope Bioware gets some EA people to help out with the shooting aspect if they want to evolve the game further, and put less focus on the stupid relationships between characters that add so little to the game. I don't want an open world like everyone is making now, but a tight experience (not a corridor like ME3). So small but vibrant areas full of interesting stuff to do.
No collection, fetch, resource quests.