I could never see myself playing Mario platformers on a touch device.
I wouldn't mind seeing real Animal Crossing and Pokemon games on phones, but they'd have to be a hell of a lot more optimized than Miitomo is. I'd also be really concerned about burning through too much battery. Nice thing about 3DS vs. phone gaming is that I don't have to worry about the 3DS's battery or it heating up enough to cook an egg when playing something mildly intensive. I imagine a marathon MH4U session on a phone would toast it within two hours at best. (iOS people with MHFU, please chime in.)