New Game+ confirmed. Not a lot of details at the moment other than no heart pickups. I'm guessing shields take more damage, enemies do more damage, enemies take less damage. I think nerfing potions/fairies would be required too, but I'm not confident about that. Maybe tougher/more enemies will show up in earlier areas. What I would like but don't expect would be new enemy/boss attack patterns and remixed dungeons. But considering the overworld/dungeon blurring of distinction I can't imagine it would be feasible.