I think we'll still be seeing this gen games until 2013, even though new consoles might come out. PS2 was still kicking it in 2006.
Wii U is probably going to share a lot of games with Vita, while the loop and PS4 move on.
I am very interested in seeing if The Last of Us is going to be a genuine serious take on the zombie apocalypse genre. There hasn't really been one. I trust Naughty Dog's ability to tell a story, I want to know if they can tell a serious story and not the camp stuff we see in Uncharted.
I don't really care much for the story as much as I would for an experiencing somewhat mimicking survival. I mean, it isn't survival if you're expected to get through it. If ND tried something interesting with the gameplay, where there wasn't a goal other than survival, maybe had procedural elements, and story was entirely dependent on actions and how characters react, then yeah, it could be great.
I'd be disappointed if it was just "we have to find x to solve y" and it was about a journey. well not really because that could be cool too. I just think a game that really embraces survival could be great. It probably won't be this game, because if the girl or guy die it would be game over and you'll never deal with the consequences. even simple things, like without a partner you can't carry as many supplies, some places couldn't be accessed alone, some other survivors react differently, etc. I'm rambling now.