Not necessarily. I mean, there's a whole range of games out there that have absolutely zero homojapual content, such as sports games and first-person shooters. Things start to get sketchy once you get past Western-developed games and dipping your feet into otherwise innocent-seeming titles such as the Street Fighter series (which features two schoolgirl characters) and the whole Japanese take on role-playing games (which frequently feature pre-pubescent looking females in highly sexualized outfits or situations).
EDIT: While I can offer no real evidence, I do have an interesting anecdote. Last Christmas I went home to visit my family and attend my cousin's wedding. Another cousin, who is in high school, came up to me the day of the ceremony interested in hearing about my experiences in Japan. After I spoke to her a bit about my job and what I had seen during my stay here so far, she confessed to being a Japanophile and started speaking about how much she loved the culture as exemplified through Full Metal Panic, Dragon Ball Z, and Naruto. Is it coincidence that my cousin has shown interest in the homojapual lifestyle, or is there a genetic link? I cannot say. In addition, the cousin who got married is ALSO a borderline Japanophile. Yet my brother and sister show absolutely no interest in degenerate Japanese subcultures (my sister is an art major so she did visit me here because she wanted to look at temples and sculpture firsthand but that's another thing entirely).