I love how you can run off course in this game and still find things to do.
I planned on hitting up the Vault Tec headquarters to find out where other vaults are located, and got sidetracked searching in downtown DC. Found a hotel couldn't get up to the upper level so I left and hit the hospital down the road. Burned through the super mutants and and the top level of the hospital found a door outside with a passage way back to the top level of the hotel I couldn't get into. Went inside and hit the Reilly's Ranges side mission. Took a long ass time too fighting my way to the top of the building where the rangers were located. Got to the top, helped all the rangers escape, and now have to find the camp so I can get my reward!
The nice thing I hit paradise falls right before I went on this epic sidequest, speeched my way into the place without having to get any slaves, and talked to the guy about giving him the chinese assault rifles. I found about a good 10 of them in the hotel fighting my way to the rangers and gave them away. I better get some sweet ass gear from this guy for giving him 20 chinese assault rifles or I'm blowing his head off with my shotty!
I feel sorry for the people who just blow through the main quest and do nothing else. There are so many cool subplots in the wasteland which you miss out on if you don't search around.