So I went back a few saves on my PC copy to "max" out my megaton experience before destroying it.
Here's what I did:
1) I stole the Sheriff's key to get the bobblehead in his house.
2) Late night, when the bar is not crowded (both the ghoul and the chick that sells rooms were asleep), I blasted off Moriarity's head, and then killed the rest of the bar workers. I took their keys and opened the fridge and got a shitload of caps. A patron sleeping upstairs attacked me. I murdered him and got maybe my BEST prize: a combat shotgun that holds 10 rounds. I also stole everything worth a nice price.
3) At the general items/gun shop, I did the 2 easy quests (Walmart and rad poisoning), and then I killed the shop owner and her guard. I stoll all the shit she was selling. I sold the stuff I didn't want back to the 3 remaining vendors in town (Doc, Restauraunt outside and inside). When you kill someone, you get access to all the shit they are selling.
4) I murdered the doc, stole all his money and the medicine. It is all worth good money.
5) I sold and murdered the in-door restaurant dude. I murdered him at night, when he's selling drugs, because he has more money then. I stole his stash and resold it once I got to Tenpenny Tower.
6) I hired the mercenary/party member in town for 1000 caps. I already have over 3000.
7) Right before leaving town, I blasted off the Sheriff's head to get his pretty decent Chinese Assault Rifle.
I raped Megaton like a cheap whore before I made it a crater. I rule.